ISSCC 2004 / SESSION 12 / BIOMICROSYSTEMS / 12 . 3 12 . 3 A 0 . 18 μ m CMOS 10 - 6 lux Bioluminescence Detection System - on - Chip
نویسندگان
چکیده
Bioluminescence whereby light is emitted as a result of a chemical reaction offers several advantages over other assay methods, such as fluorescence, including low background and the utilization of reagents with extended shelf life [1]. Also, since no filters or excitation sources are needed, lab-on-chip integration is considerably easier. Of special interest are luciferase-based assay methods with a 560nm emission peak that are used to detect pathogens and proteins, perform gene expression and regulation studies, and sequence DNA. Today’s commercial luminescence detection systems use expensive, cooled CCD-based camera setups and require many microliter volumes of costly reagents due to the high loss in their optical paths.
منابع مشابه
ISSCC 2009 / SESSION 20 / SENSORS AND MEMS / 20 . 8 20 . 8 A 0 . 25 μ m Logarithmic CMOS Imager for Emissivity -
Challenges in the design of solid-state imagers for industrial measurement and control include: high image resolution, wide temperature range, adequate temperature resolution, high measurement speed, thermal stability of the sensor chip, and most importantly, low cost. However, they have the inherent disadvantage that their temperature information is strongly dependent on the emissivity of the ...
متن کاملISSCC 2004 / SESSION 17 / MEMS AND SENSORS / 17 . 3 17 . 3 A 2 . 5 V 14 - bit Σ ∆ CMOS - SOI Capacitive Accelerometer
Low cost high precision MEMS accelerometers with near μg resolution and stability are needed in a number of applications ranging from GPS-augmented inertial navigation systems to guidance and stabilization of satellites and spacecrafts [1]. This paper presents a truly 14b Σ∆ modulator interface IC for a highresolution SOI capacitive accelerometer fabricated in a simple stictionless process that...
متن کاملISSCC 2009 / SESSION 3 / MICROPROCESSOR TECHNOLOGIES / 3 . 1 3 . 1 A 45 nm 8 - Core
The next-generation enterprise Xeon server processor consists of eight dualthreaded 64b Nehalem cores and a shared L3 cache. The system interface includes two on-chip memory controllers and supports multiple system topologies. Figure 3.1.1 shows the processor block diagram. This design has 2.3B transistors and is implemented in 45nm CMOS using metal-gate high-κ dielectric transistors and nine C...
متن کاملThree-Dimensional Dielectrophoresis Device with Integrated Actuating and Impedance Sensing
................................................................................................................................................................3 INTRODUCTION .......................................................................................................................................................4 THEORY..................................................................
متن کاملISSCC 2005 / SESSION 21 / TD : RF TRENDS : ABOVE - IC INTEGRATION AND MM - WAVE / 21 . 8 21 . 8 A 114 GHz VCO in 0 . 13 μ m CMOS Technology
Millimeter wave (MMW) VCO design is motivated by the need for the ever-increasing frequency and bandwidth of communication applications. Most previously reported W-band (75 to 110GHz) and D-band (110 to 170GHz) VCOs are realized in InP HEMT or HBT technology [1-3] due to excellent transistor performances. Recently, some millimeter-wave Si-based VCOs were reported with high power consumption [5-...
متن کامل